3pxd
From Proteopedia
(Difference between revisions)
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| - | [[Image:3pxd. | + | [[Image:3pxd.png|left|200px]] |
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021473589</ref><ref group="xtra">PMID:020516115</ref><ref group="xtra">PMID:015133503</ref><ref group="xtra">PMID:015133502</ref><ref group="xtra">PMID:012427738</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Coquelle, N.]] | [[Category: Coquelle, N.]] | ||
[[Category: Glover, J N.M.]] | [[Category: Glover, J N.M.]] | ||
[[Category: Green, R.]] | [[Category: Green, R.]] | ||
| + | [[Category: Brca1 protein]] | ||
| + | [[Category: Brct tandem repeat]] | ||
| + | [[Category: Missense]] | ||
| + | [[Category: Nuclear protein]] | ||
| + | [[Category: Phospho-peptide binding]] | ||
| + | [[Category: Phosphopeptide recognition]] | ||
| + | [[Category: Protein binding]] | ||
Revision as of 05:32, 15 June 2011
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: R1835P
Template:ABSTRACT PUBMED 21473589
About this Structure
3pxd is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Coquelle N, Green R, Glover JN. Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition. Biochemistry. 2011 Apr 7. PMID:21473589 doi:10.1021/bi2003795
- Lee MS, Green R, Marsillac SM, Coquelle N, Williams RS, Yeung T, Foo D, Hau DD, Hui B, Monteiro AN, Glover JN. Comprehensive analysis of missense variations in the BRCT domain of BRCA1 by structural and functional assays. Cancer Res. 2010 Jun 15;70(12):4880-90. Epub 2010 Jun 1. PMID:20516115 doi:10.1158/0008-5472.CAN-09-4563
- Williams RS, Lee MS, Hau DD, Glover JN. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat Struct Mol Biol. 2004 Jun;11(6):519-25. Epub 2004 May 9. PMID:15133503 doi:http://dx.doi.org/10.1038/nsmb776
- Clapperton JA, Manke IA, Lowery DM, Ho T, Haire LF, Yaffe MB, Smerdon SJ. Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer. Nat Struct Mol Biol. 2004 Jun;11(6):512-8. Epub 2004 May 9. PMID:15133502 doi:10.1038/nsmb775
- Williams RS, Glover JN. Structural consequences of a cancer-causing BRCA1-BRCT missense mutation. J Biol Chem. 2003 Jan 24;278(4):2630-5. Epub 2002 Nov 8. PMID:12427738 doi:10.1074/jbc.M210019200
