3nu0

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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Cody, V.]]
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[[Category: Cyclized inhibitor]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Oxidoreductase hdhfr-264-nadph]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 05:32, 15 June 2011

Template:STRUCTURE 3nu0

Design, Synthesis, Biological Evaluation and X-ray Crystal Structure of Novel Classical 6,5,6-TricyclicBenzo[4,5]thieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors

Template:ABSTRACT PUBMED 21550809

About this Structure

3nu0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhang X, Zhou X, Kisliuk RL, Piraino J, Cody V, Gangjee A. Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors. Bioorg Med Chem. 2011 Apr 9. PMID:21550809 doi:10.1016/j.bmc.2011.03.067

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