3o5n

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'''Unreleased structure'''
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[[Image:3o5n.jpg|left|200px]]
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The entry 3o5n is ON HOLD until Paper Publication
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{{STRUCTURE_3o5n| PDB=3o5n | SCENE= }}
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Authors: Saupe, J., Roske, Y., Schillinger, C., Kamdem, N., Radetzki, S., Diehl, A., Oschkinat, H., Krause, G., Heinemann, U., Rademann, J.
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===Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders===
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Description: Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:35:20 2010''
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{{ABSTRACT_PUBMED_21626699}}
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==About this Structure==
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[[3o5n]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O5N OCA].
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==Reference==
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<ref group="xtra">PMID:021626699</ref><references group="xtra"/>
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[[Category: Mus musculus]]
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[[Category: Diehl, A.]]
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[[Category: Heinemann, U.]]
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[[Category: Kamdem, N.]]
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[[Category: Krause, G.]]
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[[Category: Oschkinat, H.]]
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[[Category: Rademann, J.]]
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[[Category: Radetzki, S.]]
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[[Category: Roske, Y.]]
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[[Category: Saupe, J.]]
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[[Category: Schillinger, C.]]
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[[Category: Gkap]]
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[[Category: Pdz domain]]
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[[Category: Postsynaptic density]]
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[[Category: Protein binding]]
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[[Category: Protein-protein interaction]]

Revision as of 06:14, 15 June 2011

Template:STRUCTURE 3o5n

Tetrahydroquinoline carboxylates are potent inhibitors of the Shank PDZ domain, a putative target in autism disorders

Template:ABSTRACT PUBMED 21626699

About this Structure

3o5n is a 8 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Saupe J, Roske Y, Schillinger C, Kamdem N, Radetzki S, Diehl A, Oschkinat H, Krause G, Heinemann U, Rademann J. Discovery, Structure-Activity Relationship Studies, and Crystal Structure of Nonpeptide Inhibitors Bound to the Shank3 PDZ Domain. ChemMedChem. 2011 May 27. doi: 10.1002/cmdc.201100094. PMID:21626699 doi:10.1002/cmdc.201100094

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