3roc
From Proteopedia
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- | + | [[Image:3roc.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3roc", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
+ | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
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+ | {{STRUCTURE_3roc| PDB=3roc | SCENE= }} | ||
- | + | ===Crystal structure of human p38 alpha complexed with a pyrimidinone compound=== | |
- | + | ||
+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_21620699}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 21620699 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_21620699}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3roc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROC OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:021620699</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Mitogen-activated protein kinase]] | ||
+ | [[Category: Shieh, H S.]] | ||
+ | [[Category: Xing, L.]] | ||
+ | [[Category: Transferase]] | ||
+ | [[Category: Transferase-transferase inhibitor complex]] |
Revision as of 06:16, 15 June 2011
Crystal structure of human p38 alpha complexed with a pyrimidinone compound
Template:ABSTRACT PUBMED 21620699
About this Structure
3roc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Devadas B, Selness SR, Xing L, Madsen HM, Marrufo LD, Shieh H, Messing DM, Yang JZ, Morgan HM, Anderson GD, Webb EG, Zhang J, Devraj RV, Monahan JB. Substituted N-aryl-6-pyrimidinones: A new class of potent, selective, and orally active p38 MAP kinase inhibitors. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3856-60. Epub 2011 May 8. PMID:21620699 doi:10.1016/j.bmcl.2011.05.006