2f8m

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(New page: 200px<br /><applet load="2f8m" size="350" color="white" frame="true" align="right" spinBox="true" caption="2f8m, resolution 2.087&Aring;" /> '''Ribose 5-phosphate ...)
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Revision as of 17:30, 29 January 2008


2f8m, resolution 2.087Å

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Ribose 5-phosphate isomerase from Plasmodium falciparum

Overview

The structure of ribose 5-phosphate isomerase from Plasmodium falciparum, PFE0730c, has been determined by molecular replacement at 2.09 angstroms, resolution. The enzyme, which catalyzes the isomerization reaction that, interconverts ribose 5-phosphate and ribulose 5-phosphate, is a member of, the pentose phosphate pathway. The P. falciparum enzyme belongs to the, ribose 5-phosphate isomerase A family, Pfam family PF06562 (DUF1124), and, is structurally similar to other members of the family.

About this Structure

2F8M is a Single protein structure of sequence from Plasmodium falciparum 3d7 with as ligand. Active as Ribose-5-phosphate isomerase, with EC number 5.3.1.6 Full crystallographic information is available from OCA.

Reference

Structure of ribose 5-phosphate isomerase from Plasmodium falciparum., Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):427-31. Epub 2006 Apr 12. PMID:16682767

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