Gramicidin
From Proteopedia
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| - | [[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. | + | [[Gramicidin]] (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria ''Bacillus brevis''. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. |
| + | GCDN S is an antibiotic | ||
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
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== 3D Structures of Gramicidin == | == 3D Structures of Gramicidin == | ||
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| + | ''Update June 2011'' | ||
===Gramicidin A=== | ===Gramicidin A=== | ||
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===Gramicidin D=== | ===Gramicidin D=== | ||
| - | [[2xdc]], [[1w5u]], [[1bdw]], [[1al4]], [[1alx]], [[1alz]] – GCDN D<br /> | + | [[2xdc]], [[1w5u]], [[1bdw]], [[1al4]], [[1alx]], [[1alz]], [[2y5m]], [[2y6n]] – GCDN D<br /> |
[[3lml]], [[2izq]] - GCDN D + iodide<br /> | [[3lml]], [[2izq]] - GCDN D + iodide<br /> | ||
[[1c4d]] - GCDN D + CsCl | [[1c4d]] - GCDN D + CsCl | ||
| + | |||
| + | ===Gramicidin S=== | ||
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| + | [[1tk2]] – GCDN S + subtilisin savinase – ''Bacillus lentus'' | ||
Revision as of 07:07, 15 June 2011
Image:2xdc.png
Crystal Structure of Gramicidin, 2xdc
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Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria Bacillus brevis. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. GCDN S is an antibiotic
3D Structures of Gramicidin
Update June 2011
Gramicidin A
1nt5, 1nt6, 1nrm, 1nru, 1ng8, 1kqe, 1jno, 1jo3, 1jo4, 1mic, 1mag, 1grm - GCDN A – NMR
1tkq - GCDN A + mini-GCDN A – NMR
1av2 - GCDN A + CsCl
1gmk - GCDN A + KCNS
Gramicidin D
2xdc, 1w5u, 1bdw, 1al4, 1alx, 1alz, 2y5m, 2y6n – GCDN D
3lml, 2izq - GCDN D + iodide
1c4d - GCDN D + CsCl
Gramicidin S
1tk2 – GCDN S + subtilisin savinase – Bacillus lentus
