Neurexin
From Proteopedia
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''Update June 2011'' | ''Update June 2011'' | ||
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| - | === α-NRXN === | ||
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| - | [[2h0b]] - bα-NRXN-1 LNS2 – bovine<br /> | ||
| - | [[2r16]] - bα-NRXN-1 LNS 4<br /> | ||
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| - | === β-NRXN === | ||
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| - | [[3mw2]] – mβ-NRXN-1 +splice insert 4 – mouse<br /> | ||
| - | [[3bod]] - mβ-NRXN-1<br /> | ||
| - | [[3bop]] - mβ-NRXN-2d4<br /> | ||
| - | [[3mw3]], [[2r1b]] - rβ-NRXN-2 +splice insert 4 – rat<br /> | ||
| - | [[2r1b]] - rβ-NRXN-1 +splice insert 4<br /> | ||
| - | [[2r1d]] - rβ-NRXN-1 +Ca<br /> | ||
| - | [[1c4r]] - rβ-NRXN-1<br /> | ||
| - | [[3mw4]] - mβ-NRXN-3<br /> | ||
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| - | === NRXN+NLGN === | ||
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| - | [[2xb6]], [[2wqz]] – rβ-NRXN-1 +hNLGN-4 cholinesterase domain<br /> | ||
| - | [[3b3q]] - hNRXN-1 LNS domain+mNLGN-1 cholinesterase domain<br /> | ||
| - | [[3biw]] - rβ-NRXN-1 +rNLGN-1 cholinesterase domain<br /> | ||
===NRXN=== | ===NRXN=== | ||
Revision as of 11:09, 16 June 2011
Neurexins (NRXN) are a family of presynaptic proteins which bind to the postsynaptic Neuroligin (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6. The images at the left and at the right correspond to one representative NRXN, i.e. the crystal structure of mouse β-neurexin 1 (3bod).
For Structural Analysis of Neurexin, See: Neuroligin-Neurexin Interaction
3D Structures of Neurexin
Update June 2011
NRXN
3mw2 – mNRXN-1α LNS domain+splice insert 4 – mouse
3bod, 3bop - mNRXN-1α LNS domain
3mw3, 2r1b - rNRXN-1α LNS domain+splice insert 4 – rat
2r16 - rNRXN-1α LNS domain+Ca
1c4r - rNRXN-1α LNS domain
3mw4 - mNRXN-1α LNS domain
2h0b - bNRXN-1α LNS2 domain – bovine
3asi - bNRXN-1α LNS25-EGF3-LNS6 domains
NRXN+NLGN
2xb6, 2wqz – rNRXN-1α LNS domain +hNLGN-4 cholinesterase domain
3b3q - hNRXN-1α LNS domain+mNLGN-4 cholinesterase domain
3biw - rNRXN-1α LNS domain+rNLGN-1 cholinesterase domain
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, David Canner, Joel L. Sussman, Jaime Prilusky
