3qgw
From Proteopedia
(Difference between revisions)
m (Protected "3qgw" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | + | [[Image:3qgw.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3qgw", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
| + | --> | ||
| + | {{STRUCTURE_3qgw| PDB=3qgw | SCENE= }} | ||
| - | + | ===Crystal Structure of ITK kinase bound to an inhibitor=== | |
| - | + | ||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_21391610}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21391610 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_21391610}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | [[3qgw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGW OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021391610</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific protein-tyrosine kinase]] | ||
| + | [[Category: Brown, K.]] | ||
| + | [[Category: Cheetham, G M.T.]] | ||
| + | [[Category: Protein kinase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 16:36, 22 June 2011
Crystal Structure of ITK kinase bound to an inhibitor
Template:ABSTRACT PUBMED 21391610
About this Structure
3qgw is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Charrier JD, Miller A, Kay DP, Brenchley G, Twin HC, Collier PN, Ramaya S, Keily SB, Durrant SJ, Knegtel RM, Tanner AJ, Brown K, Curnock AP, Jimenez JM. Discovery and structure-activity relationship of 3-aminopyrid-2-ones as potent and selective interleukin-2 inducible T-cell kinase (Itk) inhibitors. J Med Chem. 2011 Apr 14;54(7):2341-50. Epub 2011 Mar 10. PMID:21391610 doi:10.1021/jm101499u
