Thermolysin
From Proteopedia
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[[Image:3dnz.jpg|left|200px|thumb|Crystal Structure of Thermolysin [[3dnz]]]] | [[Image:3dnz.jpg|left|200px|thumb|Crystal Structure of Thermolysin [[3dnz]]]] | ||
| - | {{STRUCTURE_3dnz| PDB=3dnz | SIZE=300| SCENE=Thermolysin/Cv/1 |right|CAPTION=Thermolysin [[3dnz]] }} | + | {{STRUCTURE_3dnz| PDB=3dnz | SIZE=300| SCENE=Thermolysin/Cv/1 |right|CAPTION=Thermolysin complex with Ca and Zn ions [[3dnz]] }} |
[[Thermolysin]] (TML) is a thermostable metalloproteinase enzyme from ''Bacillus thermoproteolyticus''. It catalyzes the hydrolysis of peptide bonds containing hydrophobic residues. The images at the left and at the right correspond to one representative Thermolysin ([[3dnz]]). | [[Thermolysin]] (TML) is a thermostable metalloproteinase enzyme from ''Bacillus thermoproteolyticus''. It catalyzes the hydrolysis of peptide bonds containing hydrophobic residues. The images at the left and at the right correspond to one representative Thermolysin ([[3dnz]]). | ||
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== 3D Structures of Thermolysin == | == 3D Structures of Thermolysin == | ||
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Revision as of 10:08, 23 June 2011
Thermolysin (TML) is a thermostable metalloproteinase enzyme from Bacillus thermoproteolyticus. It catalyzes the hydrolysis of peptide bonds containing hydrophobic residues. The images at the left and at the right correspond to one representative Thermolysin (3dnz).
Contents |
3D Structures of Thermolysin
Update June 2011
Thermolysin
2whz, 3fvp, 3dnz, 3do0, 3do1, 3do2, 2g4z, 2a7g, 1gxw, 1kei, 1l3f, 1tlx, 2tlx, 8tln, 3p7p, 3p7q, 3p7r, 3p7s, 3p7t, 3p7u, 3p7v, 3p7w – TML
3ls7 - TML residues 233-548
1trl - TML residues 255-316 – NMR
3fxs, 3fbo, 3eim, 1lna, 1lnb, 1lnc, 1lnd, 1lne, 1lnf - TML residues 233-548+metal ion replacing Ca
TML+transition state analog
1tlp, 1tmn, 2tmn, 4tmn, 5tmn – TML+transition state analog
TML+ amino acid
1kl6 – TML+ alanine
TML+ dipeptide
2wi0, 3tmn – TML+ dipeptide
3fgd - TML residues 233-548+dipeptide
TML+inhibitor
1fjo, 1fj3, 1fjq, 1fjt, 1fju, 1fjv, 1fjw, 4tli, 5tli, 6tli, 7tli, 8tli, 1tli, 2tli, 3tli – TML soaked in organic solvents
3fv4, 3fxp, 3flf, 3fb0, 3fcq, 3f28, 3f2p – TML residues 233-548+inhibitor
3fwd, 3for, 1y3g, 1zdp, 1z9g, 1pes, 1pe7, 1pe8, 1os0, 1kto, 1ks7, 1kro, 1kr6, 1kkk, 1kjo, 1kjp, 1qf0, 1qf1, 1qf2, 1hyt, 1thl, 6tmn, 7tln, 4tln, 5tln, 1pe5 – TML+inhibitor
