User:User:Marcia Ivonne Peña Paz
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
<Structure load='2KDK' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='2KDK' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
| - | It is part of the transcriptional/translational feed back loop of the circadian timing system. | + | It is part of the transcriptional/translational feed back loop of the circadian timing system. |
| - | + | ||
| - | + | ||
<scene name='User:Marcia_Ivonne_Peña_Paz/workbench/Bmal1/Bmal2_scene1/1'>TextToBeDisplayed</scene> | <scene name='User:Marcia_Ivonne_Peña_Paz/workbench/Bmal1/Bmal2_scene1/1'>TextToBeDisplayed</scene> | ||
| + | |||
| + | It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. | ||
| + | The heterodimer binds to E-box promoter elements of target genes. It modulates the expression of the genes ''Cry 1/2'', ''Per 1/2/3'', ''Dbp'', ''Rorα'', ''Pparα'', ''Namt'', ''Ccg'', ''MyoD'', ''CKIε''. | ||
Revision as of 15:18, 23 June 2011
BMAL_1
Brain and muscle Arnt like 1. Also known as MOP3
|
It is part of the transcriptional/translational feed back loop of the circadian timing system.
It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. The heterodimer binds to E-box promoter elements of target genes. It modulates the expression of the genes Cry 1/2, Per 1/2/3, Dbp, Rorα, Pparα, Namt, Ccg, MyoD, CKIε.
