User:User:Marcia Ivonne Peña Paz
From Proteopedia
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Revision as of 15:39, 23 June 2011
BMAL_1
Brain and muscle Arnt like 1. Also known as MOP3
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It is part of the transcriptional/translational feed back loop of the circadian timing system.
It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. The heterodimer binds to E-box promoter elements of target genes. It modulates the expression of the genes Cry 1/2, Per 1/2/3, Dbp, Rorα, Pparα, Namt, Ccg, MyoD, CKIε.
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