User:User:Marcia Ivonne Peña Paz
From Proteopedia
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Brain and muscle Arnt like 1. Also known as MOP3 | Brain and muscle Arnt like 1. Also known as MOP3 | ||
| - | + | It is part of the transcriptional/translational feed back loop of the circadian timing system. | |
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| - | It is part of the transcriptional/translational feed back loop of the circadian timing system. | + | |
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It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. | It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. | ||
| - | The heterodimer binds to E-box promoter elements of target genes. It modulates the expression of the genes ''Cry 1/2'', ''Per 1/2/3'', ''Dbp'', ''Rorα'', ''Pparα'', ''Namt'', ''Ccg'', ''MyoD'', ''CKIε''. | + | The heterodimer binds to E-box promoter elements of target genes, . It modulates the expression of the genes ''Cry 1/2'', ''Per 1/2/3'', ''Dbp'', ''Rorα'', ''Pparα'', ''Namt'', ''Ccg'', ''MyoD'', ''CKIε''. |
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Revision as of 07:34, 24 June 2011
BMAL_1
Brain and muscle Arnt like 1. Also known as MOP3
It is part of the transcriptional/translational feed back loop of the circadian timing system.
It forms an heterodimer with CLOCK or NPAS2 and both translocate into the nucleus. The heterodimer binds to E-box promoter elements of target genes, . It modulates the expression of the genes Cry 1/2, Per 1/2/3, Dbp, Rorα, Pparα, Namt, Ccg, MyoD, CKIε.
