Group:MUZIC:ZASP

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	doi: 10.1083/jcb.146.2.465		doi: 10.1083/jcb.146.2.465
	http://jcb.rupress.org/content/146/2/465.full		http://jcb.rupress.org/content/146/2/465.full
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Revision as of 08:44, 24 June 2011

Z-disk alternatively spliced PDZ-motif (ZASP) protein

is a component protein of the striated muscle Z-disk and a member of the enigma family of proteins. Like most enigma family members, it possess an N-terminal PDZ domain and three C-terminal LIM domains. The structure of the N-terminal PDZ domain has been solved (PDB ID: 1RGW)

spinqualitylabelsall models Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

. The PDZ domain has recently been characterized to bind a very C-terminal class III motif in myotilin and myozenin, two other Z-disk members prominent during myofibrillogenesis and sarcomerogenesis.

doi: 10.1083/jcb.146.2.465 http://jcb.rupress.org/content/146/2/465.full

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