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Group:MUZIC:ZASP

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'''Z-disk alternatively spliced PDZ-motif (ZASP) protein'''
'''Z-disk alternatively spliced PDZ-motif (ZASP) protein'''
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is a component protein of the striated muscle Z-disk and a member of the [[enigma family]] of proteins. Like most enigma family members, it possess an N-terminal PDZ domain and three C-terminal LIM domains. The structure of the N-terminal PDZ domain has been solved (PDB ID: 1RGW) <Structure load='1rgw' size='300' frame='true' align='right' caption='Insert caption here' scene='User:Adekunle_Onipe/workbench/ZASP/Zasp_pdz_domain/1' />. The PDZ domain has recently been characterized to bind a very C-terminal class III motif in [http://proteopedia.org/wiki/index.php/User:Denisa_Mullerova/workbench/Myotilin] and [[myozenin]], two other Z-disk members prominent during [[myofibrillogenesis]] and [[sarcomerogenesis]].
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is a component protein of the striated muscle Z-disk and a member of the [[enigma family]] of proteins. Like most enigma family members, it possess an N-terminal PDZ domain and three C-terminal LIM domains. The structure of the N-terminal PDZ domain has been solved (PDB ID: 1RGW) <Structure load='1rgw' size='300' frame='true' align='right' caption='Insert caption here' scene='User:Adekunle_Onipe/workbench/ZASP/Zasp_pdz_domain/1' />. The PDZ domain has recently been characterized to bind a very C-terminal class III motif in myotilin [http://proteopedia.org/wiki/index.php/User:Denisa_Mullerova/workbench/Myotilin] and [[myozenin]], two other Z-disk members prominent during [[myofibrillogenesis]] and [[sarcomerogenesis]].
doi: 10.1083/jcb.146.2.465
doi: 10.1083/jcb.146.2.465
http://jcb.rupress.org/content/146/2/465.full
http://jcb.rupress.org/content/146/2/465.full
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Revision as of 08:52, 24 June 2011

Z-disk alternatively spliced PDZ-motif (ZASP) protein

is a component protein of the striated muscle Z-disk and a member of the enigma family of proteins. Like most enigma family members, it possess an N-terminal PDZ domain and three C-terminal LIM domains. The structure of the N-terminal PDZ domain has been solved (PDB ID: 1RGW)

Insert caption here

Drag the structure with the mouse to rotate
. The PDZ domain has recently been characterized to bind a very C-terminal class III motif in myotilin [1] and myozenin, two other Z-disk members prominent during myofibrillogenesis and sarcomerogenesis.

doi: 10.1083/jcb.146.2.465 http://jcb.rupress.org/content/146/2/465.full


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Adekunle Onipe, Nikos Pinotsis, Michal Harel, Jaime Prilusky

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