Group:MUZIC:Titin
From Proteopedia
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| - | + | [[Image:Titin.jpg|100px|left|thumb| Mechanical stability and differentially conserved physical-chemical properties of titin Ig-domains. ''(2009)'' '''Proteins''']] | |
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Revision as of 09:35, 24 June 2011
Contents |
Titin
Titin (also known as connectin or smitin) is the largest protein in human proteome. Is' size varies from 1,5 to approximately 4 MegaDaltons.
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Z-disc portion of titin
portion of titin [1] [2] [3] [4] [5] [6] [7]
Function
Image:Titin.jpg
Mechanical stability and differentially conserved physical-chemical properties of titin Ig-domains. (2009) Proteins
Solved structures
Further reading:
- ↑ Ca2+-independent binding of an EF-hand domain to a novel motif in the alpha-actinin-titin complex. PMID 11573089
- ↑ Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk. PMID 16407954
- ↑ The Ig doublet Z1Z2: a model system for the hybrid analysis of conformational dynamics in Ig tandems from titin. PMID 16962974
- ↑ Third filament diseases.PMID 19181097
- ↑ The Z-disk diseases.PMID 19181098
- ↑ Mechanical stability and differentially conserved physical-chemical properties of titin Ig-domains. PMID 19003986
- ↑ Titin-based mechanical signalling in normal and failing myocardium. PMID 19639676
