1lb3
From Proteopedia
(New page: 200px<br /> <applet load="1lb3" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lb3, resolution 1.21Å" /> '''Structure of recomb...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1LB3 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]] with SO4, CD and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1LB3 OCA]]. | + | 1LB3 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]] with SO4, CD and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Sites: NCL, SS1, SS2 and SS3. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1LB3 OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: iron storage]] | [[Category: iron storage]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:10:22 2007'' |
Revision as of 10:05, 30 October 2007
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Structure of recombinant mouse L chain ferritin at 1.2 A resolution
Overview
The first ferritin structure refined at the atomic level has been achieved, on recombinant mouse L-chain apoferritin (rMoLF) crystals. These latter, diffract to 1.2 A resolution under cryogenic conditions. When cryo-cooling, the sample, the thermal disorder usually observed at room temperature is, reduced and the low-temperature structure reveals several details, concerning the protein putative active sites and their properties. Within, the pores built up by the molecular three-fold symmetry axes, the iron, entry route to the ferritin cavity, residues H118, D131 and E134, exhibit, alternate conformations associated with the binding of partially hydrated, cadmium ions, a metal used as a crystallization agent. At the mineral, ferrihydrite nucleation center, the electron density maps ... [(full description)]
About this Structure
1LB3 is a [Single protein] structure of sequence from [Mus musculus] with SO4, CD and GOL as [ligands]. Structure known Active Sites: NCL, SS1, SS2 and SS3. Full crystallographic information is available from [OCA].
Reference
Structural description of the active sites of mouse L-chain ferritin at 1.2 A resolution., Granier T, Langlois d'Estaintot B, Gallois B, Chevalier JM, Precigoux G, Santambrogio P, Arosio P, J Biol Inorg Chem. 2003 Jan;8(1-2):105-11. Epub 2002 Sep 6. PMID:12459904
Page seeded by OCA on Tue Oct 30 12:10:22 2007
