2y1e

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(New page: '''Unreleased structure''' The entry 2y1e is ON HOLD until Paper Publication Authors: Henriksson, L.M., Larsson, A.M.S., Bergfors, T., Bjorkelid, C., Unge, T., Mowbray, S.L., Jones, T.A...)
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'''Unreleased structure'''
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[[Image:2y1e.jpg|left|200px]]
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The entry 2y1e is ON HOLD until Paper Publication
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{{STRUCTURE_2y1e| PDB=2y1e | SCENE= }}
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Authors: Henriksson, L.M., Larsson, A.M.S., Bergfors, T., Bjorkelid, C., Unge, T., Mowbray, S.L., Jones, T.A.
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===X-RAY STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, DXR, RV2870C, FROM MYCOBACTERIUM TUBERCULOSIS, IN COMPLEX WITH MANGANESE.===
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Description: X-ray structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Rv2870c, from Mycobacterium tuberculosis, in complex with manganese.
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:17:31 2010''
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{{ABSTRACT_PUBMED_21678907}}
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==About this Structure==
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[[2y1e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y1E OCA].
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==Reference==
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<ref group="xtra">PMID:021678907</ref><ref group="xtra">PMID:016790937</ref><ref group="xtra">PMID:017491006</ref><references group="xtra"/>
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[[Category: 1-deoxy-D-xylulose-5-phosphate reductoisomerase]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Bergfors, T.]]
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[[Category: Bjorkelid, C.]]
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[[Category: Henriksson, L M.]]
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[[Category: Jones, T A.]]
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[[Category: Larsson, A M.S.]]
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[[Category: Mowbray, S L.]]
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[[Category: Unge, T.]]
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[[Category: Doxp/mep pathway]]
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[[Category: Oxidoreductase]]

Revision as of 06:01, 29 June 2011

Image:2y1e.jpg

Template:STRUCTURE 2y1e

X-RAY STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, DXR, RV2870C, FROM MYCOBACTERIUM TUBERCULOSIS, IN COMPLEX WITH MANGANESE.

Template:ABSTRACT PUBMED 21678907

About this Structure

2y1e is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Andaloussi M, Henriksson LM, Wieckowska A, Lindh M, Bjorkelid C, Larsson AM, Suresh S, Iyer H, Srinivasa BR, Bergfors T, Unge T, Mowbray SL, Larhed ML, Jones AT, Karlen AB. Design, Synthesis and X-ray Crystallographic Studies of alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase. J Med Chem. 2011 Jun 16. PMID:21678907 doi:10.1021/jm2000085
  • Henriksson LM, Bjorkelid C, Mowbray SL, Unge T. The 1.9 A resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target. Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):807-13. Epub 2006, Jun 20. PMID:16790937 doi:10.1107/S0907444906019196
  • Henriksson LM, Unge T, Carlsson J, Aqvist J, Mowbray SL, Jones TA. Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis. J Biol Chem. 2007 Jul 6;282(27):19905-16. Epub 2007 May 9. PMID:17491006 doi:10.1074/jbc.M701935200

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