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Group:MUZIC:Nebulin
From Proteopedia
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<StructureSection load='1ark' size='500' side='right' caption='NMR structure of the SH3 domain of Nebulin' scene='User:Marie-Cecile_Pelissier/Workbench/Nebulin/Barrel/2'>Nebulin (UniProt ID P20929 [http://www.uniprot.org/uniprot/P20929]) is one of the giant muscle-specific proteins. It is a very large protein (600-900 kDa) which has many binding partners throughout its sequence. It is involved in the structural integrity of the sarcomeres and is linked to many signalling pathways crucial for the maintenance of the sarcomere.</StructureSection> | <StructureSection load='1ark' size='500' side='right' caption='NMR structure of the SH3 domain of Nebulin' scene='User:Marie-Cecile_Pelissier/Workbench/Nebulin/Barrel/2'>Nebulin (UniProt ID P20929 [http://www.uniprot.org/uniprot/P20929]) is one of the giant muscle-specific proteins. It is a very large protein (600-900 kDa) which has many binding partners throughout its sequence. It is involved in the structural integrity of the sarcomeres and is linked to many signalling pathways crucial for the maintenance of the sarcomere.</StructureSection> | ||
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| - | == Domains == | + | ==Function== |
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| + | == Domains and interactions== | ||
[[Image:Neb.png|Modular organisation of Nebulin|400px|right|thumb|]] | [[Image:Neb.png|Modular organisation of Nebulin|400px|right|thumb|]] | ||
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The Nebulin SH3 domain adopts a ß-Barrel <scene name='User:Marie-Cecile_Pelissier/Workbench/Nebulin/Barrel/2'>fold</scene>. | The Nebulin SH3 domain adopts a ß-Barrel <scene name='User:Marie-Cecile_Pelissier/Workbench/Nebulin/Barrel/2'>fold</scene>. | ||
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| + | ==Refrences== | ||
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Revision as of 12:08, 1 July 2011
Contents |
Introduction
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Function
Domains and interactions
Glutamic rich region
Nebulin modules
Serine rich region
SH3 domain
The Nebulin SH3 domain adopts a ß-Barrel .
Refrences
Interactions
References
Proteopedia Page Contributors and Editors (what is this?)
Marie-Cecile Pelissier, Michal Harel, Jaime Prilusky, Nikos Pinotsis
