3qti

(Difference between revisions)

Revision as of 18:46, 6 July 2011

3qti is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Tiedt R, Degenkolbe E, Furet P, Appleton BA, Wagner S, Schoepfer J, Buck E, Ruddy D, Monahan JE, Jones MD, Blank J, Haasen D, Drueckes P, Wartmann M, McCarthy C, Sellers WR, Hofmann F. A drug resistance screen using a selective MET inhibitor reveals a spectrum of mutations that partially overlap with activating mutations found in cancer patients. Cancer Res. 2011 Jun 22. PMID:21697284 doi:10.1158/0008-5472.CAN-10-4433

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-'''Unreleased structure'''
+[[Image:3qti.jpg|left|200px]]
-The entry 3qti is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_3qti", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3qti|  PDB=3qti  |  SCENE=  }}
-Authors: Appleton, B.A.
+===c-Met Kinase in Complex with NVP-BVU972===
-Description: c-Met Kinase in Complex with NVP-BVU972
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_21697284}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 21697284 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_21697284}}
+==About this Structure==
+[[3qti]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QTI OCA].
+==Reference==
+<ref group="xtra">PMID:021697284</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Receptor protein-tyrosine kinase]]
+[[Category: Appleton, B A.]]
+[[Category: Kinase]]
+[[Category: Transerase]]
+[[Category: Transferase-transferase inhibitor complex]]