Group:MUZIC:XIN
From Proteopedia
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Xin directly binds F-actin <ref name="pmid15454575">. | Xin directly binds F-actin <ref name="pmid15454575">. | ||
| + | <blockquote> | ||
| + | This section complements the article on [http://www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb106_1.html Poly(A) Polymerase] in the | ||
| + | [http://www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] Series. See also [[Teaching Scenes, Tutorials, and Educators' Pages]]. | ||
| + | </blockquote> | ||
| + | |||
| + | ==Additional Resources== | ||
| + | For additional information, see: [[Translation]] <br/> | ||
| + | For additional examples of transferases, see: [[Transferase]] | ||
== References == | == References == | ||
<references/><nowiki> | <references/><nowiki> | ||
<references /> | <references /> | ||
Revision as of 00:17, 12 July 2011
Xin actin-binding repeat-containing protein 1 (Alternative name: Cardiomyopathy-associated protein 1) is coded by the gene (Synonyms:CMYA1, XIN) and has an actin-binding domain (ABD). It crosslinks actin filaments and participates in anchoring of membrane proteins. Intraexogic splicing leads to a least three different isoforms.
Sequence Annotation
Interactions with other proteins/ Function
Xin and Mena/VASP colocalize with filamin c in [intercalated discs][1](ICD, structure at the end of the myocytes that transduce force from the myofibrils via the cell membranes to the extracelluar matrix and neighboring cells) in the adult heart [1].
Xin directly binds the EVH1 domain proteins Mena and VASP [2]
