3rkz
From Proteopedia
(Difference between revisions)
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- | + | [[Image:3rkz.jpg|left|200px]] | |
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+ | The line below this paragraph, containing "STRUCTURE_3rkz", creates the "Structure Box" on the page. | ||
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+ | {{STRUCTURE_3rkz| PDB=3rkz | SCENE= }} | ||
- | + | ===Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model.=== | |
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+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_21715165}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 21715165 is the PubMed ID number. | ||
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+ | {{ABSTRACT_PUBMED_21715165}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3rkz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKZ OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:021715165</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Bloom, J D.]] | ||
+ | [[Category: Boschelli, F.]] | ||
+ | [[Category: Dushin, R G.]] | ||
+ | [[Category: Golas, J M.]] | ||
+ | [[Category: Johnson, M.]] | ||
+ | [[Category: Levin, J I.]] | ||
+ | [[Category: Li, Z.]] | ||
+ | [[Category: Liu, H.]] | ||
+ | [[Category: Lucas, J.]] | ||
+ | [[Category: Nikitenko, A.]] | ||
+ | [[Category: Nittoli, T.]] | ||
+ | [[Category: Olland, A.]] | ||
+ | [[Category: Otteng, M.]] | ||
+ | [[Category: Vogan, E.]] | ||
+ | [[Category: Zapf, C W.]] | ||
+ | [[Category: Atp binding domain]] | ||
+ | [[Category: Atp-binding]] | ||
+ | [[Category: Chaperone]] | ||
+ | [[Category: Chaperone-chaperone inhibitor complex]] | ||
+ | [[Category: Nucleotide-binding]] | ||
+ | [[Category: Phosphoprotein]] | ||
+ | [[Category: Stress response]] |
Revision as of 07:35, 13 July 2011
Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model.
Template:ABSTRACT PUBMED 21715165
About this Structure
3rkz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zapf CW, Bloom JD, Li Z, Dushin RG, Nittoli T, Otteng M, Nikitenko A, Golas JM, Liu H, Lucas J, Boschelli F, Vogan E, Olland A, Johnson M, Levin JI. Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model. Bioorg Med Chem Lett. 2011 Jun 27. PMID:21715165 doi:10.1016/j.bmcl.2011.05.102
Categories: Homo sapiens | Bloom, J D. | Boschelli, F. | Dushin, R G. | Golas, J M. | Johnson, M. | Levin, J I. | Li, Z. | Liu, H. | Lucas, J. | Nikitenko, A. | Nittoli, T. | Olland, A. | Otteng, M. | Vogan, E. | Zapf, C W. | Atp binding domain | Atp-binding | Chaperone | Chaperone-chaperone inhibitor complex | Nucleotide-binding | Phosphoprotein | Stress response