2c49
From Proteopedia
(New page: 200px<br /> <applet load="2c49" size="450" color="white" frame="true" align="right" spinBox="true" caption="2c49, resolution 1.92Å" /> '''CRYSTAL STRUCTURE O...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2C49 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ | + | 2C49 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]] with MG, ADN and ANP as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C49 OCA]]. |
==Reference== | ==Reference== | ||
Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family., Arnfors L, Hansen T, Schonheit P, Ladenstein R, Meining W, Acta Crystallogr D Biol Crystallogr. 2006 Sep;62(Pt 9):1085-97. Epub 2006, Aug 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16929110 16929110] | Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family., Arnfors L, Hansen T, Schonheit P, Ladenstein R, Meining W, Acta Crystallogr D Biol Crystallogr. 2006 Sep;62(Pt 9):1085-97. Epub 2006, Aug 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16929110 16929110] | ||
| - | [[Category: | + | [[Category: Methanocaldococcus jannaschii]] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Arnfors, L.]] | [[Category: Arnfors, L.]] | ||
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[[Category: transferase]] | [[Category: transferase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:15:16 2007'' |
Revision as of 10:10, 30 October 2007
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CRYSTAL STRUCTURE OF METHANOCALDOCOCCUS JANNASCHII NUCLEOSIDE KINASE- AN ARCHAEAL MEMBER OF THE RIBOKINASE FAMILY
Overview
Nucleoside kinase from the hyperthermophilic archaeon Methanocaldococcus, jannaschii (MjNK) is a member of the ribokinase family. In the presence of, ATP and Mg(2+), MjNK is able to catalyze the phosphorylation of a variety, of nucleosides, including inosine, cytidine, guanosine and adenosine., Here, the crystal structure of MjNK, the first structure of an archaeal, representative of the ribokinase family, is presented. The structure was, solved using the multiple-wavelength anomalous dispersion technique., Three-dimensional structures of the unliganded enzyme and a complex of, MjNK, an ATP analogue and adenosine were determined to 1.7 and 1.9 A, resolution, respectively. Each subunit comprises an alpha/beta-domain and, a smaller lid domain and has an overall fold characteristic of the, ... [(full description)]
About this Structure
2C49 is a [Single protein] structure of sequence from [Methanocaldococcus jannaschii] with MG, ADN and ANP as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family., Arnfors L, Hansen T, Schonheit P, Ladenstein R, Meining W, Acta Crystallogr D Biol Crystallogr. 2006 Sep;62(Pt 9):1085-97. Epub 2006, Aug 19. PMID:16929110
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