3ras
From Proteopedia
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| - | [[Image:3ras. | + | [[Image:3ras.png|left|200px]] |
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[[Category: Prasad, B V.V.]] | [[Category: Prasad, B V.V.]] | ||
[[Category: Song, Y.]] | [[Category: Song, Y.]] | ||
| + | [[Category: 1-deoxy-d-xylulose 5-phosphate reductoisomerase]] | ||
| + | [[Category: Doxp/mep pathway]] | ||
| + | [[Category: Isoprene biosynthesis]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Oxidoreductase-inhibitor complex]] | ||
Revision as of 05:41, 20 July 2011
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor
Template:ABSTRACT PUBMED 21561155
About this Structure
3ras is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Deng L, Diao J, Chen P, Pujari V, Yao Y, Cheng G, Crick DC, Prasad BV, Song Y. Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR and Crystallographic Studies. J Med Chem. 2011 May 11. PMID:21561155 doi:10.1021/jm200363d
