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3qpn
From Proteopedia
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Revision as of 05:43, 20 July 2011
Structure of PDE10-inhibitor complex
Template:ABSTRACT PUBMED 21650160
About this Structure
3qpn is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Helal CJ, Kang Z, Hou X, Pandit J, Chappie TA, Humphrey JM, Marr ES, Fennell KF, Chenard LK, Fox C, Schmidt CJ, Williams RD, Chapin DS, Siuciak J, Lebel L, Menniti F, Cianfrogna J, Fonseca KR, Nelson FR, O'Connor R, Macdougall M, McDowell L, Liras S. Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia. J Med Chem. 2011 Jun 8. PMID:21650160 doi:10.1021/jm2001508
