3sjt
From Proteopedia
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- | + | [[Image:3sjt.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3sjt", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
+ | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
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+ | {{STRUCTURE_3sjt| PDB=3sjt | SCENE= }} | ||
- | + | ===Crystal structure of human arginase I in complex with the inhibitor Me-ABH, Resolution 1.60 A, twinned structure=== | |
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+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_21728378}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 21728378 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_21728378}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3sjt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SJT OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:021728378</ref><ref group="xtra">PMID:016141327</ref><references group="xtra"/> | ||
+ | [[Category: Arginase]] | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Christianson, D W.]] | ||
+ | [[Category: Costanzo, L Di.]] | ||
+ | [[Category: 2-amino-6-borono-2-methylhexanoic acid]] | ||
+ | [[Category: Abh inhibitor derivative]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
+ | [[Category: Twinning]] |
Revision as of 06:42, 20 July 2011
Crystal structure of human arginase I in complex with the inhibitor Me-ABH, Resolution 1.60 A, twinned structure
Template:ABSTRACT PUBMED 21728378
About this Structure
3sjt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Ilies M, Di Costanzo L, Dowling DP, Thorn KJ, Christianson DW. Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design. J Med Chem. 2011 Jul 18. PMID:21728378 doi:10.1021/jm200443b
- Di Costanzo L, Sabio G, Mora A, Rodriguez PC, Ochoa AC, Centeno F, Christianson DW. Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13058-63. Epub 2005 Sep 2. PMID:16141327