1cwc

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:7966126</ref><references group="xtra"/>	+	<ref group="xtra">PMID:007966126</ref><ref group="xtra">PMID:015299416</ref><ref group="xtra">PMID:008073029</ref><ref group="xtra">PMID:008263916</ref><ref group="xtra">PMID:008421501</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
		+	[[Category: Peptidylprolyl isomerase]]
	[[Category: Mikol, V.]]		[[Category: Mikol, V.]]
		+	[[Category: Cyclophilin]]
		+	[[Category: Cyclophilin-cyclosporin complex]]
		+	[[Category: Cyclosporin some]]
		+	[[Category: Immunosuppressant]]
		+	[[Category: Isomerase-immunosuppressant complex]]

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Revision as of 05:02, 27 July 2011

Template:STRUCTURE 1cwc

Contents 1 IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN 2 About this Structure 3 See Also 4 Reference

IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN

About this Structure

1cwc is a 2 chain structure of Cyclophilin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Cyclophilin

Reference

• Papageorgiou C, Florineth A, Mikol V. Improved binding affinity for cyclophilin A by a cyclosporin derivative singly modified at its effector domain. J Med Chem. 1994 Oct 28;37(22):3674-6. PMID:7966126
• Mikol V, Duc D. Crystallization of the complex between cyclophilin A and cyclosporin derivatives: the use of cross-seeding. Acta Crystallogr D Biol Crystallogr. 1994 Jul 1;50(Pt 4):543-9. PMID:15299416 doi:10.1107/S0907444994001800
• Mikol V, Kallen J, Walkinshaw MD. The X-ray structure of (MeBm2t)1-cyclosporin complexed with cyclophilin A provides an explanation for its anomalously high immunosuppressive activity. Protein Eng. 1994 May;7(5):597-603. PMID:8073029
• Mikol V, Kallen J, Pflugl G, Walkinshaw MD. X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution. J Mol Biol. 1993 Dec 20;234(4):1119-30. PMID:8263916 doi:http://dx.doi.org/10.1006/jmbi.1993.1664
• Pflugl G, Kallen J, Schirmer T, Jansonius JN, Zurini MG, Walkinshaw MD. X-ray structure of a decameric cyclophilin-cyclosporin crystal complex. Nature. 1993 Jan 7;361(6407):91-4. PMID:8421501 doi:http://dx.doi.org/10.1038/361091a0