3oeu

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Revision as of 06:13, 27 July 2011

Template:STRUCTURE 3oeu

Structure of yeast 20S open-gate proteasome with Compound 24

Template:ABSTRACT PUBMED 20875739

About this Structure

3oeu is a 28 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

• Blackburn C, Barrett C, Blank JL, Bruzzese FJ, Bump N, Dick LR, Fleming P, Garcia K, Hales P, Hu Z, Jones M, Liu JX, Sappal DS, Sintchak MD, Tsu C, Gigstad KM. Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6581-6. Epub 2010 Sep 15. PMID:20875739 doi:10.1016/j.bmcl.2010.09.032