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Helicase
From Proteopedia
Michal Harel (Talk | contribs)
(New page: {{STRUCTURE_3fht| PDB=3fht | SIZE=300| SCENE= |right| CAPTION=Human dead box ATP-dependent RNA helicase DDX19B complex with RNA, 3fht }} '''Helicase''' (Hel) is a motor protein wh...)
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Revision as of 07:54, 27 July 2011
Helicase (Hel) is a motor protein which separates nucleic acid strands like DNA double helix or self-annealed RNA. They use ATP hydrolysis for energy. Hel falls into 5 superfamilies (SF1-SF5). Some Hel contain a Helicase and RNase D C terminal Domain (HRDC). The α-thalassemia and mental retardation X-linked syndrome helicase (ATRX ), contains an ATRX-Dnmt3-Dnmt3L (ADD) domain in which many disease-related mutations are found.
Contents |
3D structures of helicase
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Wayne Decatur, Joel L. Sussman
