3q3t
From Proteopedia
(Difference between revisions)
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- | + | [[Image:3q3t.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3q3t", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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+ | {{STRUCTURE_3q3t| PDB=3q3t | SCENE= }} | ||
- | + | ===Alkyl Amine Renin Inhibitors: Filling S1 from S3=== | |
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+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_21741239}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 21741239 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_21741239}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3q3t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q3T OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:021741239</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Renin]] | ||
+ | [[Category: McKeever, B.]] | ||
+ | [[Category: Wu, Z.]] | ||
+ | [[Category: Aspartate protease]] | ||
+ | [[Category: Glycoprotein]] | ||
+ | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
+ | [[Category: Hypertension]] | ||
+ | [[Category: Renin inhibitor]] | ||
+ | [[Category: Zymogen]] |
Revision as of 08:46, 3 August 2011
Alkyl Amine Renin Inhibitors: Filling S1 from S3
Template:ABSTRACT PUBMED 21741239
About this Structure
3q3t is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Yuan J, Simpson RD, Zhao W, Tice CM, Xu Z, Cacatian S, Jia L, Flaherty PT, Guo J, Ishchenko A, Wu Z, McKeever BM, Scott BB, Bukhtiyarov Y, Berbaum J, Panemangalore R, Bentley R, Doe CP, Harrison RK, McGeehan GM, Singh SB, Dillard LW, Baldwin JJ, Claremon DA. Biphenyl/diphenyl ether renin inhibitors: Filling the S1 pocket of renin via the S3 pocket. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4836-43. Epub 2011 Jun 17. PMID:21741239 doi:10.1016/j.bmcl.2011.06.043