3f6u

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m (Protected "3f6u" [edit=sysop:move=sysop])
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==About this Structure==
==About this Structure==
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[[3f6u]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6U OCA].
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[[3f6u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6U OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:12029084</ref><ref group="xtra">PMID:9003757</ref><references group="xtra"/>
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<ref group="xtra">PMID:012029084</ref><ref group="xtra">PMID:009003757</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bajaj, S P.]]
[[Category: Bajaj, S P.]]
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[[Category: Schmidt, A E.]]
[[Category: Schmidt, A E.]]
[[Category: Underwood, M C.]]
[[Category: Underwood, M C.]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Blood coagulation]]
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[[Category: Disease mutation]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Egf-like domain]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Hydroxylation]]
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[[Category: Plasma calcium binding]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Re-refinement]]
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[[Category: Revised version of the coordinate file pdb 1aut]]
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[[Category: Serine protease]]
[[Category: Serine protease]]
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[[Category: Thrombophilia]]
 
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[[Category: Zymogen]]
 

Revision as of 04:49, 10 August 2011

Template:STRUCTURE 3f6u

Crystal structure of human Activated Protein C (APC) complexed with PPACK

Template:ABSTRACT PUBMED 12029084

About this Structure

3f6u is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Schmidt AE, Padmanabhan K, Underwood MC, Bode W, Mather T, Bajaj SP. Thermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loops. J Biol Chem. 2002 Aug 9;277(32):28987-95. Epub 2002 May 23. PMID:12029084 doi:10.1074/jbc.M201892200
  • Mather T, Oganessyan V, Hof P, Huber R, Foundling S, Esmon C, Bode W. The 2.8 A crystal structure of Gla-domainless activated protein C. EMBO J. 1996 Dec 16;15(24):6822-31. PMID:9003757

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