3skc
From Proteopedia
(Difference between revisions)
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- | + | [[Image:3skc.jpg|left|200px]] | |
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3skc", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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+ | {{STRUCTURE_3skc| PDB=3skc | SCENE= }} | ||
- | + | ===Human B-Raf Kinase in Complex with an Amide Linked Pyrazolopyridine Inhibitor=== | |
- | + | ||
+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_21802293}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 21802293 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_21802293}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | [[3skc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SKC OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:021802293</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Non-specific serine/threonine protein kinase]] | ||
+ | [[Category: Sturgis, H L.]] | ||
+ | [[Category: Voegtli, W C.]] | ||
+ | [[Category: Atp-competitive inhibitor]] | ||
+ | [[Category: C-raf]] | ||
+ | [[Category: Kinase]] | ||
+ | [[Category: Mek]] | ||
+ | [[Category: Ra]] | ||
+ | [[Category: Transferase]] | ||
+ | [[Category: Transferase-transferase inhibitor complex]] |
Revision as of 06:13, 17 August 2011
Human B-Raf Kinase in Complex with an Amide Linked Pyrazolopyridine Inhibitor
Template:ABSTRACT PUBMED 21802293
About this Structure
3skc is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wenglowsky S, Ahrendt KA, Buckmelter AJ, Feng B, Gloor SL, Gradl S, Grina J, Hansen JD, Laird ER, Lunghofer P, Mathieu S, Moreno D, Newhouse B, Ren L, Risom T, Rudolph J, Seo J, Sturgis HL, Voegtli WC, Wen Z. Pyrazolopyridine inhibitors of B-Raf(V600E). Part 2: Structure-activity relationships. Bioorg Med Chem Lett. 2011 Jul 2. PMID:21802293 doi:10.1016/j.bmcl.2011.06.097