3p2b

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'''Unreleased structure'''
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[[Image:3p2b.jpg|left|200px]]
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The entry 3p2b is ON HOLD until Paper Publication
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{{STRUCTURE_3p2b| PDB=3p2b | SCENE= }}
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Authors: Knapp, M.S., Elling, R.A., Ornelas, E.
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===Crystal Structure of PI3K gamma with 3-(2-morpholino-6-(pyridin-3-ylamino)pyrimidin-4-yl)phenol===
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Description: Crystal Structure of PI3K gamma with 3-(2-morpholino-6-(pyridin-3-ylamino)pyrimidin-4-yl)phenol
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:22:47 2010''
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(as it appears on PubMed at http://www.pubmed.gov), where 21035331 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21035331}}
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==About this Structure==
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[[3p2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P2B OCA].
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==Reference==
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<ref group="xtra">PMID:021035331</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Elling, R A.]]
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[[Category: Knapp, M S.]]
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[[Category: Ornelas, E.]]
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[[Category: Atp binding]]
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[[Category: Lipid kinase]]
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[[Category: Pi3-kinase p110 subunit gamma]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 06:16, 17 August 2011

Image:3p2b.jpg

Template:STRUCTURE 3p2b

Crystal Structure of PI3K gamma with 3-(2-morpholino-6-(pyridin-3-ylamino)pyrimidin-4-yl)phenol

Template:ABSTRACT PUBMED 21035331

About this Structure

3p2b is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pecchi S, Renhowe PA, Taylor C, Kaufman S, Merritt H, Wiesmann M, Shoemaker KR, Knapp MS, Ornelas E, Hendrickson TF, Fantl W, Voliva CF. Identification and structure-activity relationship of 2-morpholino 6-(3-hydroxyphenyl) pyrimidines, a class of potent and selective PI3 kinase inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6895-8. Epub 2010 Oct 13. PMID:21035331 doi:10.1016/j.bmcl.2010.10.021

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