3p2b

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Revision as of 06:16, 17 August 2011

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Template:STRUCTURE 3p2b

Crystal Structure of PI3K gamma with 3-(2-morpholino-6-(pyridin-3-ylamino)pyrimidin-4-yl)phenol

Template:ABSTRACT PUBMED 21035331

About this Structure

3p2b is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Pecchi S, Renhowe PA, Taylor C, Kaufman S, Merritt H, Wiesmann M, Shoemaker KR, Knapp MS, Ornelas E, Hendrickson TF, Fantl W, Voliva CF. Identification and structure-activity relationship of 2-morpholino 6-(3-hydroxyphenyl) pyrimidines, a class of potent and selective PI3 kinase inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6895-8. Epub 2010 Oct 13. PMID:21035331 doi:10.1016/j.bmcl.2010.10.021