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3oez

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Revision as of 06:26, 17 August 2011

Template:STRUCTURE 3oez

crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain complexed with imatinib

Template:ABSTRACT PUBMED 17355866

About this Structure

3oez is a 2 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J. c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty. Structure. 2007 Mar;15(3):299-311. PMID:17355866 doi:10.1016/j.str.2007.01.015

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