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2bh1
From Proteopedia
(New page: 200px<br /> <applet load="2bh1" size="450" color="white" frame="true" align="right" spinBox="true" caption="2bh1, resolution 2.40Å" /> '''X-RAY STRUCTURE OF ...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2BH1 is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BH1 OCA]]. | + | 2BH1 is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: CAL. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BH1 OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: vibrio cholerae]] | [[Category: vibrio cholerae]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:22:26 2007'' |
Revision as of 10:17, 30 October 2007
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X-RAY STRUCTURE OF THE GENERAL SECRETION PATHWAY COMPLEX OF THE N-TERMINAL DOMAIN OF EPSE AND THE CYTOSOLIC DOMAIN OF EPSL OF VIBRIO CHOLERAE
Overview
Gram-negative bacteria use type II secretion systems for the transport of, virulence factors and hydrolytic enzymes through the outer membrane. These, sophisticated multi-protein complexes reach from the pore in the outer, membrane via the pseudopilins in the periplasm and a multi-protein, inner-membrane sub-complex, to an ATPase in the cytoplasm. The human, pathogen Vibrio cholerae uses such a secretion machinery, called the, Eps-system, for the export of its major virulence factor cholera toxin, into the intestinal tract of the human host. Here, we describe the 2.4 A, structure of the hetero-tetrameric complex of the N-terminal domain of the, ATPase EpsE and the cytoplasmic domain of the inner membrane protein EpsL, which constitute the major cytoplasmic components of the Eps-system. A, ... [(full description)]
About this Structure
2BH1 is a [Protein complex] structure of sequences from [Vibrio cholerae] with CA as [ligand]. Structure known Active Site: CAL. Full crystallographic information is available from [OCA].
Reference
The X-ray structure of the type II secretion system complex formed by the N-terminal domain of EpsE and the cytoplasmic domain of EpsL of Vibrio cholerae., Abendroth J, Murphy P, Sandkvist M, Bagdasarian M, Hol WG, J Mol Biol. 2005 May 13;348(4):845-55. PMID:15843017
Page seeded by OCA on Tue Oct 30 12:22:26 2007
Categories: Protein complex | Vibrio cholerae | Abendroth, J. | Bagdasarian, M. | Hol, W.G.J. | Murphy, P.M. | Mushtaq, A. | Sandkvist, M. | CA | Atp-binding | Eps | Gsp | Transmembrane | Transport | Type ii secretion
