We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

1h8l

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /> <applet load="1h8l" size="450" color="white" frame="true" align="right" spinBox="true" caption="1h8l, resolution 2.60&Aring;" /> '''DUCK CARBOXYPEPTIDA...)
Line 8: Line 8:
==About this Structure==
==About this Structure==
-
1H8L is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Lophonetta_specularioides Lophonetta specularioides]] with NAG, SO4, ZN and GEM as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1H8L OCA]].
+
1H8L is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Anas_specularioides Anas specularioides]] with NAG, SO4, ZN and GEM as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: ZN. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1H8L OCA]].
==Reference==
==Reference==
The crystal structure of the inhibitor-complexed carboxypeptidase D domain II and the modeling of regulatory carboxypeptidases., Aloy P, Companys V, Vendrell J, Aviles FX, Fricker LD, Coll M, Gomis-Ruth FX, J Biol Chem. 2001 May 11;276(19):16177-84. Epub 2001 Feb 14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11278909 11278909]
The crystal structure of the inhibitor-complexed carboxypeptidase D domain II and the modeling of regulatory carboxypeptidases., Aloy P, Companys V, Vendrell J, Aviles FX, Fricker LD, Coll M, Gomis-Ruth FX, J Biol Chem. 2001 May 11;276(19):16177-84. Epub 2001 Feb 14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11278909 11278909]
-
[[Category: Lophonetta specularioides]]
+
[[Category: Anas specularioides]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Aviles, F.X.]]
[[Category: Aviles, F.X.]]
Line 27: Line 27:
[[Category: zinc-dependent protease]]
[[Category: zinc-dependent protease]]
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 19:11:31 2007''
+
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:23:20 2007''

Revision as of 10:18, 30 October 2007

Image:1h8l.gif

1h8l, resolution 2.60Å

Drag the structure with the mouse to rotate

DUCK CARBOXYPEPTIDASE D DOMAIN II IN COMPLEX WITH GEMSA

Overview

The three-dimensional crystal structure of duck carboxypeptidase D domain, II has been solved in a complex with the peptidomimetic inhibitor, guanidinoethylmercaptosuccinic acid, occupying the specificity pocket., This structure allows a clear definition of the substrate binding sites, and the substrate funnel-like access. The structure of domain II is the, only one available from the regulatory carboxypeptidase family and can be, used as a general template for its members. Here, it has been used to, model the structures of domains I and III from the former protein and of, human carboxypeptidase E. The models obtained show that the overall, topology is similar in all cases, the main differences being local and, because of insertions in non-regular loops. In both carboxypeptidase D, domain ... [(full description)]

About this Structure

1H8L is a [Single protein] structure of sequence from [Anas specularioides] with NAG, SO4, ZN and GEM as [ligands]. Structure known Active Site: ZN. Full crystallographic information is available from [OCA].

Reference

The crystal structure of the inhibitor-complexed carboxypeptidase D domain II and the modeling of regulatory carboxypeptidases., Aloy P, Companys V, Vendrell J, Aviles FX, Fricker LD, Coll M, Gomis-Ruth FX, J Biol Chem. 2001 May 11;276(19):16177-84. Epub 2001 Feb 14. PMID:11278909

Page seeded by OCA on Tue Oct 30 12:23:20 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h8l"
Personal tools