452d

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(New page: 200px<br /><applet load="452d" size="350" color="white" frame="true" align="right" spinBox="true" caption="452d, resolution 1.6&Aring;" /> '''ACRIDINE BINDING TO D...)
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Revision as of 19:44, 29 January 2008


452d, resolution 1.6Å

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ACRIDINE BINDING TO DNA

About this Structure

452D is a Protein complex structure of sequences from [1] with and as ligands. Full crystallographic information is available from OCA.

Reference

Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960

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