2c0t
From Proteopedia
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m (Protected "2c0t" [edit=sysop:move=sysop]) |
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016216497</ref><ref group="xtra">PMID:015109663</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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[[Category: Li, B.]] | [[Category: Li, B.]] | ||
[[Category: Loew, A.]] | [[Category: Loew, A.]] | ||
| - | [[Category: Alternative initiation]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Palmitate]] | [[Category: Palmitate]] | ||
| - | [[Category: Phosphorylation]] | ||
[[Category: Sh2 domain]] | [[Category: Sh2 domain]] | ||
[[Category: Sh3 domain]] | [[Category: Sh3 domain]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | [[Category: Tyrosine-protein kinase]] | ||
Revision as of 05:59, 24 August 2011
SRC FAMILY KINASE HCK WITH BOUND INHIBITOR A-641359
Template:ABSTRACT PUBMED 16216497
About this Structure
2c0t is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Burchat A, Borhani DW, Calderwood DJ, Hirst GC, Li B, Stachlewitz RF. Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection. Bioorg Med Chem Lett. 2006 Jan 1;16(1):118-22. Epub 2005 Oct 10. PMID:16216497 doi:10.1016/j.bmcl.2005.09.039
- Borhani DW, Calderwood DJ, Friedman MM, Hirst GC, Li B, Leung AK, McRae B, Ratnofsky S, Ritter K, Waegell W. A-420983: a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection. Bioorg Med Chem Lett. 2004 May 17;14(10):2613-6. PMID:15109663 doi:10.1016/j.bmcl.2004.02.101
Categories: Homo sapiens | Transferase | Borhani, D W. | Burchat, A. | Calderwood, D J. | Hirst, G C. | Li, B. | Loew, A. | Atp-binding | Kinase | Lipoprotein | Myristate | Nucleotide-binding | Palmitate | Sh2 domain | Sh3 domain
