3sie

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'''Unreleased structure'''
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[[Image:3sie.jpg|left|200px]]
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The entry 3sie is ON HOLD
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{{STRUCTURE_3sie| PDB=3sie | SCENE= }}
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Authors: Chen,T.T., Chen,T., Xu,Y.C.
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===Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors===
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Description: Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors
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{{ABSTRACT_PUBMED_21714539}}
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==About this Structure==
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[[3sie]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SIE OCA].
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==Reference==
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<ref group="xtra">PMID:021714539</ref><references group="xtra"/>
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[[Category: 3',5'-cyclic-GMP phosphodiesterase]]
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[[Category: Homo sapiens]]
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[[Category: Chen, T.]]
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[[Category: Chen, T T.]]
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[[Category: Xu, Y C.]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Pde5a inhibitor]]

Revision as of 07:28, 24 August 2011

Image:3sie.jpg

Template:STRUCTURE 3sie

Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors

Template:ABSTRACT PUBMED 21714539

About this Structure

3sie is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Xu Z, Liu Z, Chen T, Chen T, Wang Z, Tian G, Shi J, Wang X, Lu Y, Yan X, Wang G, Jiang H, Chen K, Wang S, Xu Y, Shen J, Zhu W. Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. J Med Chem. 2011 Aug 11;54(15):5607-11. Epub 2011 Jul 14. PMID:21714539 doi:10.1021/jm200644r

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OCA

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