2qsk
From Proteopedia
(New page: 200px<br /><applet load="2qsk" size="350" color="white" frame="true" align="right" spinBox="true" caption="2qsk, resolution 1.000Å" /> '''Atomic-resolution c...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2QSK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Scytonema_varium Scytonema varium] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QSK OCA]. | + | 2QSK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Scytonema_varium Scytonema varium] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Cl Binding Site For Residue A 96'>AC1</scene>, <scene name='pdbsite=AC2:Cl Binding Site For Residue A 97'>AC2</scene> and <scene name='pdbsite=AC3:Gol Binding Site For Residue A 99'>AC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QSK OCA]. |
==Reference== | ==Reference== | ||
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[[Category: sugar binding protein]] | [[Category: sugar binding protein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 31 10:59:33 2008'' |
Revision as of 08:59, 31 January 2008
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Atomic-resolution crystal structure of the Recombinant form of Scytovirin
Overview
The crystal structures of the natural and recombinant antiviral lectin, scytovirin (SVN) were solved by single-wavelength anomalous scattering and, refined with data extending to 1.3 A and 1.0 A resolution, respectively. A, molecule of SVN consists of a single chain 95 amino acids long, with an, almost perfect sequence repeat that creates two very similar domains (RMS, deviation 0.25 A for 40 pairs of Calpha atoms). The crystal structure, differs significantly from a previously published NMR structure of the, same protein, with the RMS deviations calculated separately for the N- and, C-terminal domains of 5.3 A and 3.7 A, respectively, and a very different, relationship between the two domains. In addition, the disulfide bonding, pattern of the crystal structures differs from that described in the, previously published mass spectrometry and NMR studies.
About this Structure
2QSK is a Protein complex structure of sequences from Scytonema varium with and as ligands. Known structural/functional Sites: , and . Full crystallographic information is available from OCA.
Reference
Atomic-resolution crystal structure of the antiviral lectin scytovirin., Moulaei T, Botos I, Ziolkowska NE, Bokesch HR, Krumpe LR, McKee TC, O'Keefe BR, Dauter Z, Wlodawer A, Protein Sci. 2007 Dec;16(12):2756-60. Epub 2007 Oct 26. PMID:17965185
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