3s2o
From Proteopedia
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| - | [[Image:3s2o. | + | [[Image:3s2o.png|left|200px]] |
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==About this Structure== | ==About this Structure== | ||
| - | [[3s2o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3msm 3msm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2O OCA]. | + | [[3s2o]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3msm 3msm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2O OCA]. |
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| + | ==See Also== | ||
| + | *[[Beta secretase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Madden, J.]] | [[Category: Madden, J.]] | ||
[[Category: Smith, M A.]] | [[Category: Smith, M A.]] | ||
| + | [[Category: Alzheimer's disease]] | ||
| + | [[Category: Amyloid precursor protein secretase]] | ||
| + | [[Category: Aspartic endopeptidase]] | ||
| + | [[Category: Aspartic protease]] | ||
| + | [[Category: Aspartyl protease]] | ||
| + | [[Category: Base]] | ||
| + | [[Category: Beta-secretase]] | ||
| + | [[Category: Fluorescence polarisation]] | ||
| + | [[Category: Fragment-based drug design]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Memapsin 2]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Transmembrane]] | ||
Revision as of 05:23, 7 September 2011
Contents |
Fragment based discovery and optimisation of bace-1 inhibitors
Template:ABSTRACT PUBMED 20656487
About this Structure
3s2o is a 1 chain structure of Beta secretase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3msm. Full crystallographic information is available from OCA.
See Also
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
Categories: Homo sapiens | Memapsin 2 | Barker, J. | Godemann, R. | Hallett, D. | Kraemer, J. | Madden, J. | Smith, M A. | Alzheimer's disease | Amyloid precursor protein secretase | Aspartic endopeptidase | Aspartic protease | Aspartyl protease | Base | Beta-secretase | Fluorescence polarisation | Fragment-based drug design | Glycoprotein | Hydrolase-hydrolase inhibitor complex | Protease | Transmembrane
