3pe2

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'''Unreleased structure'''
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[[Image:3pe2.jpg|left|200px]]
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The entry 3pe2 is ON HOLD until Paper Publication
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{{STRUCTURE_3pe2| PDB=3pe2 | SCENE= }}
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Authors: Battistutta, R., Papinutto, E., Lolli, G., Pierre, F., Haddach, M., Ryckman, D.M.
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===Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011===
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Description: Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 8 11:31:41 2010''
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{{ABSTRACT_PUBMED_21870818}}
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==About this Structure==
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[[3pe2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PE2 OCA].
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==Reference==
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<ref group="xtra">PMID:021870818</ref><ref group="xtra">PMID:019432557</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Battistutta, R.]]
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[[Category: Haddach, M.]]
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[[Category: Lolli, G.]]
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[[Category: Papinutto, E.]]
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[[Category: Pierre, F.]]
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[[Category: Ryckman, D M.]]
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[[Category: Ck2-inhibitor complex]]
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[[Category: Kinase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 06:10, 7 September 2011

Image:3pe2.jpg

Template:STRUCTURE 3pe2

Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011

Template:ABSTRACT PUBMED 21870818

About this Structure

3pe2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Battistutta R, Cozza G, Pierre F, Papinutto E, Lolli G, Sarno S, O'Brien SE, Siddiqui-Jain A, Haddach M, Anderes K, Ryckman DM, Meggio F, Pinna LA. Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical stage for the treatment of cancer. Biochemistry. 2011 Aug 26. PMID:21870818 doi:10.1021/bi2008382
  • Cozza G, Mazzorana M, Papinutto E, Bain J, Elliott M, di Maira G, Gianoncelli A, Pagano MA, Sarno S, Ruzzene M, Battistutta R, Meggio F, Moro S, Zagotto G, Pinna LA. Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2. Biochem J. 2009 Jul 15;421(3):387-95. PMID:19432557 doi:10.1042/BJ20090069

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