Urokinase
From Proteopedia
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Michal Harel (Talk | contribs)
(New page: {{STRUCTURE_3ig6| PDB=3ig6 | SIZE=400| SCENE= |right|CAPTION=Human urokinase A and B chains complex with inhibitor, 3ig6 }} '''Urokinase''' (UK) is a serine protease whose principa...)
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Revision as of 07:36, 20 September 2011
Urokinase (UK) is a serine protease whose principal substrate is plasminogen – the inactive zymogen of plasmin. UK consists of 3 domains: ligand-binding domain and kringle and growth factor domains. Prourokinase (PUK) is the inactive zymogen of UK which becomes active by proteolytic cleavage.
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