Homocitrate synthase
From Proteopedia
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Michal Harel (Talk | contribs)
(New page: {{STRUCTURE_1q1p| PDB=1q1p | SIZE=300| SCENE=Cadherin/Cv/1 |right|CAPTION=Cadherin, 1q1p }} '''Homocitrate synthase''' (HS) participates in lysine biosynthesis and pyruvate metabol...)
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Revision as of 11:52, 20 September 2011
Homocitrate synthase (HS) participates in lysine biosynthesis and pyruvate metabolism. HS catalyzes the conversion of acetyl-CoA + H2O + 2-oxoglutarate to 2-hydroxybutane-1,2,4-tricarboxylate + CoA.
3D Structures of homocitrate synthase
3ivs – fyHS Lys4 – fission yeast
3ivt, 3ivu - fyHS Lys4 + 2-oxoglutaric acid
3mi3 - fyHS Lys4 + lysine
2ztj – TtHS + α-ketoglutarate – Thermus thermophilus
2zyf - TtHS + α-ketoglutarate + Mg
2ztk – TtHS + homocitrate
3a9i – TtHS + lysine
