Homocitrate synthase
From Proteopedia
(Difference between revisions)
(New page: {{STRUCTURE_1q1p| PDB=1q1p | SIZE=300| SCENE=Cadherin/Cv/1 |right|CAPTION=Cadherin, 1q1p }} '''Homocitrate synthase''' (HS) participates in lysine biosynthesis and pyruvate metabol...) |
|||
| Line 1: | Line 1: | ||
| - | + | {{STRUCTURE_3ivt| PDB=3ivt | SIZE=400| SCENE= |right|CAPTION=Fission yeast homocitrate synthase Lys4 complex with 2-oxoglutarate, [[3ivt]] }} | |
| - | {{ | + | |
'''Homocitrate synthase''' (HS) participates in lysine biosynthesis and pyruvate metabolism. HS catalyzes the conversion of acetyl-CoA + H2O + 2-oxoglutarate to 2-hydroxybutane-1,2,4-tricarboxylate + CoA. | '''Homocitrate synthase''' (HS) participates in lysine biosynthesis and pyruvate metabolism. HS catalyzes the conversion of acetyl-CoA + H2O + 2-oxoglutarate to 2-hydroxybutane-1,2,4-tricarboxylate + CoA. | ||
| Line 11: | Line 10: | ||
[[3ivt]], [[3ivu]] - fyHS Lys4 + 2-oxoglutaric acid<br /> | [[3ivt]], [[3ivu]] - fyHS Lys4 + 2-oxoglutaric acid<br /> | ||
[[3mi3]] - fyHS Lys4 + lysine<br /> | [[3mi3]] - fyHS Lys4 + lysine<br /> | ||
| - | [[ | + | [[2ztj]] – TtHS + α-ketoglutarate – ''Thermus thermophilus''<br /> |
[[2zyf]] - TtHS + α-ketoglutarate + Mg<br /> | [[2zyf]] - TtHS + α-ketoglutarate + Mg<br /> | ||
[[2ztk]] – TtHS + homocitrate<br /> | [[2ztk]] – TtHS + homocitrate<br /> | ||
[[3a9i]] – TtHS + lysine | [[3a9i]] – TtHS + lysine | ||
| + | |||
| + | [[Category:Topic Page]] | ||
Revision as of 11:54, 20 September 2011
Homocitrate synthase (HS) participates in lysine biosynthesis and pyruvate metabolism. HS catalyzes the conversion of acetyl-CoA + H2O + 2-oxoglutarate to 2-hydroxybutane-1,2,4-tricarboxylate + CoA.
3D Structures of homocitrate synthase
3ivs – fyHS Lys4 – fission yeast
3ivt, 3ivu - fyHS Lys4 + 2-oxoglutaric acid
3mi3 - fyHS Lys4 + lysine
2ztj – TtHS + α-ketoglutarate – Thermus thermophilus
2zyf - TtHS + α-ketoglutarate + Mg
2ztk – TtHS + homocitrate
3a9i – TtHS + lysine
