2x39
From Proteopedia
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m (Protected "2x39" [edit=sysop:move=sysop]) |
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STRUCTURE OF 4-AMINO-N-(4-CHLOROBENZYL)-1-(7H-PYRROLO(2,3-D) PYRIMIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE BOUND TO PKB
Template:ABSTRACT PUBMED 20151677
About this Structure
2x39 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- McHardy T, Caldwell JJ, Cheung KM, Hunter LJ, Taylor K, Rowlands M, Ruddle R, Henley A, de Haven Brandon A, Valenti M, Davies TG, Fazal L, Seavers L, Raynaud FI, Eccles SA, Aherne GW, Garrett MD, Collins I. Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt). J Med Chem. 2010 Feb 12. PMID:20151677 doi:10.1021/jm901788j
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Aherne, G W. | Brandon, A D. | Caldwell, J J. | Cheung, K M. | Collins, I. | Davies, T G. | Eccles, S A. | Fazal, L. | Garrett, M D. | Henley, A. | Hunter, L J. | Mchardy, T. | Raynaud, F I. | Rowlands, M. | Ruddle, R. | Seavers, L. | Taylor, K. | Valenti, M. | Kinase | Nucleotide-binding | Phosphoprotein | Serine/threonine-protein kinase | Transferase | Wnt signaling pathway