3r4b

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'''Unreleased structure'''
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[[Image:3r4b.jpg|left|200px]]
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The entry 3r4b is ON HOLD until Paper Publication
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{{STRUCTURE_3r4b| PDB=3r4b | SCENE= }}
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Authors: Schiffer, C.A., Nalam, M.N.L.
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===Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911===
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Description: Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911
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{{ABSTRACT_PUBMED_21896904}}
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==About this Structure==
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[[3r4b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R4B OCA].
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==Reference==
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<ref group="xtra">PMID:021896904</ref><references group="xtra"/>
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Nalam, M N.L.]]
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[[Category: Schiffer, C A.]]
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[[Category: Aid]]
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[[Category: Aspartyl protease]]
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[[Category: Drug design]]
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[[Category: Drug resistance]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Protease inhibitor]]

Revision as of 05:55, 21 September 2011

Image:3r4b.jpg

Template:STRUCTURE 3r4b

Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911

Template:ABSTRACT PUBMED 21896904

About this Structure

3r4b is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Dierynck I, Van Marck H, Van Ginderen M, Jonckers TH, Nalam MN, Schiffer CA, Raoof A, Kraus G, Picchio G. TMC310911, a Novel Human Immunodeficiency Virus Type-1 Protease Inhibitor shows in Vitro an Improved Resistance Profile and Higher Genetic Barrier to Resistance Compared with Current Protease Inhibitors. Antimicrob Agents Chemother. 2011 Sep 6. PMID:21896904 doi:10.1128/AAC.00748-11

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OCA

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