This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Semaphorin
From Proteopedia
(New page: '''Semaphorin''' (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 a...) |
|||
| Line 1: | Line 1: | ||
| - | + | {{STRUCTURE_3nvn| PDB=3nvn | SIZE=400| SCENE= |right|CAPTION=Human semaphorin 7A complex with plexin-C1, [[3nvn]] }} | |
| - | + | ||
'''Semaphorin''' (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics. | '''Semaphorin''' (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics. | ||
| + | |||
| + | {{TOC limit|limit=2}} | ||
==3D structures of semaphorin== | ==3D structures of semaphorin== | ||
| Line 24: | Line 26: | ||
[[3nvn]], [[3nvq]] – hSEMA 7A + plexin-C1 | [[3nvn]], [[3nvq]] – hSEMA 7A + plexin-C1 | ||
| + | |||
| + | [[Category:Topic Page]] | ||
Revision as of 21:45, 26 September 2011
Template:STRUCTURE 3nvn
Semaphorin (SEMA) are membrane proteins which act as axonal growth guidance molecules. SEMA act as short-range inhibitory signal. There are 8 classes of SEMA numbered 1 to 7 and V (viral). Each class has several subgroups which share similar characteristics.
3D structures of semaphorin
SEMA 3
1q47 – mSEMA 3A – mouse
SEMA 4
1olz – hSEMA 4D extracellular domain – human
3ol2 - hSEMA 4D extracellular domain + plexin-B1
SEMA 6
3afc, 3okw - mSEMA 6A extracellular domain
3al8 - mSEMA 6A + plexin-A2
