3pjc

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==Reference==
==Reference==
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<ref group="xtra">PMID:21155605</ref><references group="xtra"/>
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<ref group="xtra">PMID:021155605</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]

Revision as of 04:59, 28 September 2011

Template:STRUCTURE 3pjc

Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family

Template:ABSTRACT PUBMED 21155605

About this Structure

3pjc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Thoma G, Nuninger F, Falchetto R, Hermes E, Tavares GA, Vangrevelinghe E, Zerwes HG. Identification of a Potent Janus Kinase 3 Inhibitor with High Selectivity within the Janus Kinase Family. J Med Chem. 2010 Dec 14. PMID:21155605 doi:10.1021/jm101157q

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