3b0w
From Proteopedia
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===Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with digoxin=== | ===Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with digoxin=== | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_21733845}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21733845 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_21733845}} | ||
==About this Structure== | ==About this Structure== | ||
[[3b0w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B0W OCA]. | [[3b0w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B0W OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021733845</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ando, O.]] | [[Category: Ando, O.]] | ||
| - | [[Category: Fujita-Sato, | + | [[Category: Fujita-Sato, S.]] |
[[Category: Isobe, T.]] | [[Category: Isobe, T.]] | ||
[[Category: Isono, F.]] | [[Category: Isono, F.]] | ||
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[[Category: Orphan nuclear receptor]] | [[Category: Orphan nuclear receptor]] | ||
[[Category: Three-layered alpha helical sandwich]] | [[Category: Three-layered alpha helical sandwich]] | ||
| - | [[Category: Transcription]] | + | [[Category: Transcription-inhibitor complex]] |
Revision as of 05:01, 28 September 2011
Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with digoxin
Template:ABSTRACT PUBMED 21733845
About this Structure
3b0w is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Fujita-Sato S, Ito S, Isobe T, Ohyama T, Wakabayashi K, Morishita K, Ando O, Isono F. Structural Basis of Digoxin That Antagonizes ROR{gamma}t Receptor Activity and Suppresses Th17 Cell Differentiation and Interleukin (IL)-17 Production. J Biol Chem. 2011 Sep 9;286(36):31409-17. Epub 2011 Jul 6. PMID:21733845 doi:10.1074/jbc.M111.254003
